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< Nexium® Granules for Suspension, Sachets: 10 mg>
・Gastric ulcer, duodenal ulcer, anastomotic ulcer, Zollinger-Ellison syndrome
[Adults] The usual adult dose is 20 mg of esomeprazole made into a suspension in water at the time of use, taken orally once daily. The usual duration of administration is up to 8 weeks for gastric ulcer and anastomotic ulcer and up to 6 weeks for duodenal ulcer.
[Children] The usual doses for children aged 1 year and older are 10 mg of esomeprazole for a bodyweight of less than 20 kg and 10 to 20 mg of esomeprazole for a bodyweight of 20 kg or over, depending on symptoms, made into a suspension in water at the time of use, taken orally once daily. The usual duration of administration is up to 8 weeks for gastric ulcer and anastomotic ulcer and up to 6 weeks for duodenal ulcer.
・Reflux esophagitis
[Adults] The usual adult dose is 20 mg of esomeprazole made into a suspension in water at the time of use, taken orally once daily. The usual duration of administration is up to 8 weeks. As maintenance therapy for continually recurring/relapsing reflux esophagitis, 10 to 20 mg of esomeprazole is made into a suspension in water at the time of use and taken orally once daily.
[Children] The usual doses for children aged 1 year and older are 10 mg of esomeprazole for a bodyweight of less than 20 kg and 10 to 20 mg of esomeprazole for a bodyweight of 20 kg or over, depending on symptoms, made into a suspension in water at the time of use, taken orally once daily. The usual duration of administration is up to 8 weeks.
・Non-erosive reflux disease
[Adults] The usual adult dose is 10 mg of esomeprazole made into a suspension in water at the time of use, taken orally once daily. The usual duration of administration is up to 4 weeks.
[Children] The usual dose for children aged 1 year and older is 10 mg of esomeprazole made into a suspension in water at the time of use, taken orally once daily. The usual duration of administration is up to 4 weeks.
・Prevention of recurrence of gastric ulcer and duodenal ulcer in patients treated with non-steroidal anti-inflammatory drugs
The usual adult dose is 20 mg of esomeprazole made into a suspension in water at the time of use, taken orally once daily.
・Prevention of recurrence of gastric ulcer and duodenal ulcer in patients treated with low-dose aspirin
The usual adult dose is 20 mg of esomeprazole made into a suspension in water at the time of use, taken orally once daily.
・Adjuvant therapy for Helicobacter pylori eradication
The usual adult dose is 20 mg of esomeprazole made into a suspension in water at the time of use, concomitantly with 750 mg (potency) of amoxicillin hydrate and 200 mg (potency) of clarithromycin, taken orally twice daily for 7 days. The dose of clarithromycin may be increased appropriately as required. However, the limits on dosing are 400 mg (potency) per time and twice daily. If Helicobacter pylori eradication with triple therapy consisting of proton pump inhibitor, amoxicillin hydrate, and clarithromycin fails, the usual dose for adults of 20 mg of esomeprazole is made into a suspension in water at the time of use and taken orally, concomitantly with 750 mg (potency) of amoxicillin hydrate and 250 mg of metronidazole, twice daily for 7 days as alternative therapy.
<Nexium® Granules for Suspension, Sachets: 20 mg>
・Gastric ulcer, duodenal ulcer, anastomotic ulcer, Zollinger-Ellison syndrome
[Adults] The usual adult dose is 20 mg of esomeprazole made into a suspension in water at the time of use, taken orally once daily. The usual duration of administration is up to 8 weeks for gastric ulcer and anastomotic ulcer and up to 6 weeks for duodenal ulcer.
[Children] For infants and children with a bodyweight of 20 kg or over, the usual dose is 10 to 20 mg of esomeprazole, depending on symptoms, made into a suspension in water at the time of use, taken orally once daily. The usual duration of administration is up to 8 weeks for gastric ulcer and anastomotic ulcer and up to 6 weeks for duodenal ulcer.
・Reflux esophagitis
[Adults] The usual adult dose is 20 mg of esomeprazole made into a suspension in water at the time of use, taken orally once daily. The usual duration of administration is up to 8 weeks. As maintenance therapy for continually recurring/relapsing reflux esophagitis, 10 to 20 mg made into a suspension in water at the time of use is taken orally once daily.
[Children] For infants and children with a body weight of 20 kg or over, the usual dose is 10 to 20 mg of esomeprazole, depending on symptoms, made into a suspension in water at the time of use, taken orally once daily. The usual duration of administration is up to 8 weeks.
・Prevention of recurrence of gastric ulcer and duodenal ulcer in patients treated with non-steroidal anti-inflammatory drugs
The usual adult dose is 20 mg of esomeprazole made into a suspension in water at the time of use, taken orally once daily.
・Prevention of recurrence of gastric ulcer and duodenal ulcer in patients treated with low-dose aspirin
The usual adult dose is 20 mg of esomeprazole made into a suspension in water at the time of use, taken orally once daily.
・Adjuvant therapy for Helicobacter pylori eradication
The usual adult dose is 20 mg of esomeprazole made into a suspension in water at the time of use, concomitantly with 750 mg (potency) of amoxicillin hydrate and 200 mg (potency) of clarithromycin, taken orally twice daily for 7 days. The dose of clarithromycin may be increased appropriately as required. However, the limits on dosing are 400 mg (potency) per time and twice daily. If Helicobacter pylori eradication with triple therapy consisting of proton pump inhibitor, amoxicillin hydrate, and clarithromycin fails, the usual dose for adults of 20 mg of esomeprazole is made into a suspension in water at the time of use and taken orally, concomitantly with 750 mg (potency) of amoxicillin hydrate and 250 mg of metronidazole, twice daily for 7 days as alternative therapy.
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